Reduced in vitro T-cell responses induced by glutaraldehyde-modified allergen extracts are caused mainly by retarded internalization of dendritic cells

Although allergen-specific immunotherapy is a clinically effective therapy for IgE-mediated allergic diseases, the risk of IgE-mediated adverse effects still exists. For this reason, chemically modified allergoids have been introduced, which may destroy IgE-binding sites while T-cell activation shou...

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Detalhes bibliográficos
Main Authors: Heydenreich, Bärbel, Bellinghausen, Iris, Lorenz, Steffen, Henmar, Helene, Strand, Dennis, Würtzen, Peter A, Saloga, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403258/
https://ncbi.nlm.nih.gov/pubmed/22348538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03571.x
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