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REST regulates the pool size of the different neural lineages by restricting the generation of neurons and oligodendrocytes from neural stem/progenitor cells

REST is a master repressor of neuronal genes; however, whether it has any role during nervous system development remains largely unknown. Here, we analyzed systematically the role of REST in embryonic stem cells and multipotent neural stem/progenitor (NS/P) cells, including neurogenic and gliogenic...

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Bibliografiske detaljer
Main Authors: Covey, Matthew V., Streb, Jeffrey W., Spektor, Roman, Ballas, Nurit
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403100/
https://ncbi.nlm.nih.gov/pubmed/22791895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.074765
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