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Differential Deployment of REST and CoREST Promotes Glial Subtype Specification and Oligodendrocyte Lineage Maturation

BACKGROUND: The repressor element-1 (RE1) silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) is a master transcriptional regulator that binds to numerous genomic RE1 sites where it acts as a molecular scaffold for dynamic recruitment of modulatory and epigenetic cofactors,...

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Autors principals: Abrajano, Joseph J., Qureshi, Irfan A., Gokhan, Solen, Zheng, Deyou, Bergman, Aviv, Mehler, Mark F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766030/
https://ncbi.nlm.nih.gov/pubmed/19888342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007665
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