Development of operational models of receptor activation including constitutive receptor activity and their use to determine the efficacy of the chemokine CCL17 at the CC chemokine receptor CCR4

BACKGROUND AND PURPOSE: The operational model provides a key conceptual framework for the analysis of pharmacological data. However, this model does not include constitutive receptor activity, a frequent phenomenon in modern pharmacology, particularly in recombinant systems. Here, we developed exten...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Slack, RJ, Hall, DA
التنسيق: Artigo
اللغة:Inglês
منشور في: Blackwell Publishing Ltd 2012
الموضوعات:
Research Papers
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402803/
https://ncbi.nlm.nih.gov/pubmed/22335621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01901.x
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة