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Caveolin-1 Deficiency Protects from Pulmonary Fibrosis by Modulating Epithelial Cell Senescence in Mice
Idiopathic pulmonary fibrosis is associated with a decreased expression of caveolin-1 (cav-1), yet its role remains unclear. To investigate the role of cav-1, we induced pulmonary fibrosis in wild-type (WT) and cav-1–deficient (cav-1(−/−)) mice using intratracheal instillation of bleomycin. Contrary...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Thoracic Society
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402795/ https://ncbi.nlm.nih.gov/pubmed/22362388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0349OC |
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