Inhibitory effects of sevoflurane on pacemaking activity of sinoatrial node cells in guinea-pig heart

BACKGROUND AND PURPOSE: The volatile anaesthetic sevoflurane affects heart rate in clinical settings. The present study investigated the effect of sevoflurane on sinoatrial (SA) node automaticity and its underlying ionic mechanisms. EXPERIMENTAL APPROACH: Spontaneous action potentials and four ionic...

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Bibliografiske detaljer
Main Authors: Kojima, Akiko, Kitagawa, Hirotoshi, Omatsu-Kanbe, Mariko, Matsuura, Hiroshi, Nosaka, Shuichi
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2012
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402776/
https://ncbi.nlm.nih.gov/pubmed/22356456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01914.x
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