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BRG1 and NRG1 Form a Novel Feedback Circuit Regulating C. albicans Hypha Formation and Virulence

In the opportunistic fungal pathogen Candida albicans both cellular morphology and the capacity to cause disease are regulated by the transcriptional repressor Nrg1p. One of the genes repressed by Nrg1p is BRG1, which encodes a putative GATA family transcription factor. Deletion of both copies of th...

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Autors principals: Cleary, Ian A., Lazzell, Anna L., Monteagudo, Carlos, Thomas, Derek P., Saville, Stephen P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402693/
https://ncbi.nlm.nih.gov/pubmed/22757963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08127.x
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