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BRG1 and NRG1 Form a Novel Feedback Circuit Regulating C. albicans Hypha Formation and Virulence

In the opportunistic fungal pathogen Candida albicans both cellular morphology and the capacity to cause disease are regulated by the transcriptional repressor Nrg1p. One of the genes repressed by Nrg1p is BRG1, which encodes a putative GATA family transcription factor. Deletion of both copies of th...

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Bibliografiske detaljer
Main Authors: Cleary, Ian A., Lazzell, Anna L., Monteagudo, Carlos, Thomas, Derek P., Saville, Stephen P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402693/
https://ncbi.nlm.nih.gov/pubmed/22757963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08127.x
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