Efficacy of a Genetically Engineered Candida albicans tet-NRG1 Strain as an Experimental Live Attenuated Vaccine against Hematogenously Disseminated Candidiasis

We report on the efficacy of the genetically engineered Candida albicans tet-NRG1 strain as an experimental live, attenuated vaccine against disseminated candidiasis in both immunocompetent and immunodeficient mice mostly dependent on T-cell immunity. This experimental vaccination model may represen...

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Detalhes bibliográficos
Main Authors: Saville, Stephen P., Lazzell, Anna L., Chaturvedi, Ashok K., Monteagudo, Carlos, Lopez-Ribot, Jose L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650868/
https://ncbi.nlm.nih.gov/pubmed/19144791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00480-08
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