Amyloid and metabolic PET imaging of cognitively normal adults with Alzheimer’s parents

This study examines the relationship between fibrillar amyloid-beta (Aβ) deposition and reduced glucose metabolism, a proxy for neuronal dysfunction, in cognitively normal (NL) individuals with a parent affected by late-onset Alzheimer’s disease (AD). Forty-seven 40–80 year-old NL received Positron...

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Autori principali: Mosconi, Lisa, Rinne, Juha O., Tsui, Wai H., Murray, John, Li, Yi, Glodzik, Lidia, McHugh, Pauline, Williams, Schantel, Cummings, Megan, Pirraglia, Elizabeth, Goldsmith, Stanley J., Vallabhajosula, Shankar, Scheinin, Noora, Viljanen, Tapio, Nagren, Kjell, de Leon, Mony J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402654/
https://ncbi.nlm.nih.gov/pubmed/22503001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.03.002
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