Increased fibrillar amyloid-β burden in normal individuals with a family history of late-onset Alzheimer’s

Having a parent affected with late-onset Alzheimer's disease (LOAD) is a major risk factor among cognitively normal (NL) individuals. This (11)C-Pittsburgh Compound B (PiB)-PET study examines whether NL individuals with LOAD parents show increased fibrillar amyloid-beta (Aβ) deposition, a hallm...

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Detalhes bibliográficos
Main Authors: Mosconi, Lisa, Rinne, Juha O., Tsui, Wai H., Berti, Valentina, Li, Yi, Wang, Huiyu, Murray, John, Scheinin, Noora, Någren, Kjell, Williams, Schantel, Glodzik, Lidia, De Santi, Susan, Vallabhajosula, Shankar, de Leon, Mony J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851906/
https://ncbi.nlm.nih.gov/pubmed/20231448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914141107
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