Increased fibrillar amyloid-β burden in normal individuals with a family history of late-onset Alzheimer’s

Having a parent affected with late-onset Alzheimer's disease (LOAD) is a major risk factor among cognitively normal (NL) individuals. This (11)C-Pittsburgh Compound B (PiB)-PET study examines whether NL individuals with LOAD parents show increased fibrillar amyloid-beta (Aβ) deposition, a hallm...

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Bibliographic Details
Main Authors: Mosconi, Lisa, Rinne, Juha O., Tsui, Wai H., Berti, Valentina, Li, Yi, Wang, Huiyu, Murray, John, Scheinin, Noora, Någren, Kjell, Williams, Schantel, Glodzik, Lidia, De Santi, Susan, Vallabhajosula, Shankar, de Leon, Mony J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851906/
https://ncbi.nlm.nih.gov/pubmed/20231448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914141107
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