Characterization of a series of 4-aminoquinolines that stimulate caspase-7 mediated cleavage of TDP-43 and inhibit its function

Lignende værker

• Ubiquilin-2 (UBQLN2) binds with high affinity to the C-terminal region of TDP-43 and modulates TDP-43 levels in H4 cells: characterization of inhibition by nucleic acids and 4-aminoquinolines
  af: Cassel, Joel A., et al.
  Udgivet: (2013)
• TDP-43-induced Death Is Associated with Altered Regulation of BIM and Bcl-xL and Attenuated by Caspase-mediated TDP-43 Cleavage
  af: Suzuki, Hiroaki, et al.
  Udgivet: (2011)
• The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels
  af: Salazar, Dominique A., et al.
  Udgivet: (2015)
• Development of a Novel Nonradiometric Assay for Nucleic Acid Binding to TDP-43 Suitable for High-Throughput Screening Using AlphaScreen(®) Technology
  af: CASSEL, JOEL A., et al.
  Udgivet: (2010)
• Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
  af: Zhang, Yong-Jie, et al.
  Udgivet: (2009)