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ADP Ribosylation by PARP-1 Suppresses HOXB7 Transcriptional Activity

Interactions with cofactors regulate transcriptional activity and also help HOX proteins to achieve the specificity required for transcriptional regulation of target genes. In this study, we describe a novel protein/protein interaction of HOXB7 with poly (ADP-ribose) polymerase-1 (PARP-1) that invol...

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Detalhes bibliográficos
Main Authors: Wu, Xinyan, Ellmann, Stephan, Rubin, Ethel, Gil, Minchan, Jin, Kideok, Han, Liangfeng, Chen, Hexin, Kwon, Erika M., Guo, Jianhui, Ha, Hyo Chol, Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402478/
https://ncbi.nlm.nih.gov/pubmed/22844406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040644
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