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Solution Structures of the Prototypical 18 kDa Translocator Protein Ligand, PK 11195, Elucidated with (1)H/(13)C NMR Spectroscopy and Quantum Chemistry
[Image: see text] Eighteen kilodalton translocator protein (TSPO) is an important target for drug discovery and for clinical molecular imaging of brain and peripheral inflammatory processes. PK 11195 [1a; 1-(2-chlorophenyl)-N-methyl-(1-methylpropyl)-3-isoquinoline carboxamide] is the major prototypi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402376/ https://ncbi.nlm.nih.gov/pubmed/22860199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn3000108 |
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