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Decreased Arteriolar Tetrahydrobiopterin is Linked to Superoxide Generation from Nitric Oxide Synthase in Mice Fed High Salt

OBJECTIVE: Impaired endothelium-dependent arteriolar dilation in mice fed high salt is due to local oxidation of nitric oxide (NO) by superoxide anion (O(2)(-)). We explored the possibility that “uncoupled” endothelial nitric oxide synthase (eNOS) is the source of this O(2)(-). METHODS: Levels of L-...

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Bibliografiset tiedot
Päätekijät: Nurkiewicz, Timothy R., Wu, Guoyao, Li, Peng, Boegehold, Matthew A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402363/
https://ncbi.nlm.nih.gov/pubmed/20163541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1549-8719.2009.00014.x
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