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Virus-specific CD8(+) T cells up-regulate PD-1 expression during acute Friend retrovirus infection but are highly cytotoxic and control virus replication
It was recently reported that inhibitory molecules such as PD-1 were up-regulated on CD8(+) T cells during acute Friend retrovirus infection, and that the cells were prematurely exhausted and dysfunctional in vitro. The current study confirms that most activated CD8(+) T cells up-regulated expressio...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402334/ https://ncbi.nlm.nih.gov/pubmed/21873525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101612 |
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