Left ventricular failure produces profound lung remodeling and pulmonary hypertension in mice: heart failure causes severe lung disease

Chronic left ventricular failure causes pulmonary congestion with increased lung weight and type-2 pulmonary hypertension. Understanding the molecular mechanisms for type-2 pulmonary hypertension and the development of novel treatments for this condition requires a robust experimental animal model a...

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Detalhes bibliográficos
Main Authors: Chen, Yingjie, Guo, Haipeng, Xu, Dachun, Xu, Xin, Wang, Huan, Hu, Xinli, Lu, Zhongbing, Kwak, Dongmin, Xu, Yawei, Gunther, Roland, Huo, Yuqing, Weir, E. Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402091/
https://ncbi.nlm.nih.gov/pubmed/22508832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.186072
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