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TIMP-2 targets tumor associated-myeloid suppressor cells with effects in cancer immune dysfunction and angiogenesis
Angiogenesis and inflammation are important therapeutic targets in non-small cell lung cancer (NSCLC). It is well known that proteolysis mediated by matrix metalloproteinases (MMPs) promotes angiogenesis and inflammation in the tumor microenvironment. Here, the effects of the MMP-inhibitor TIMP-2 on...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402087/ https://ncbi.nlm.nih.gov/pubmed/22735808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3182619c8e |
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