Age and Geographical Distribution in Families with BRCA1/BRCA2 Mutations in the Slovak Republic

Molecular diagnostics of hereditary breast and/or ovarian cancer is mainly based on detection of BRCA1 and BRCA2 germline mutations in suspected families. The aim of the study was to determine the frequency, age and geographical distribution in 130 Slovak hereditary breast and ovarian cancer (HBOC)...

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Bibliografiske detaljer
Main Authors: Ciernikova, Sona, Tomka, Miroslav, Kovac, Michal, Stevurkova, Viola, Zajac, Vladimir
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401926/
https://ncbi.nlm.nih.gov/pubmed/20223009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-4-1-7
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