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Age and Geographical Distribution in Families with BRCA1/BRCA2 Mutations in the Slovak Republic

Molecular diagnostics of hereditary breast and/or ovarian cancer is mainly based on detection of BRCA1 and BRCA2 germline mutations in suspected families. The aim of the study was to determine the frequency, age and geographical distribution in 130 Slovak hereditary breast and ovarian cancer (HBOC)...

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Detalhes bibliográficos
Main Authors: Ciernikova, Sona, Tomka, Miroslav, Kovac, Michal, Stevurkova, Viola, Zajac, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401926/
https://ncbi.nlm.nih.gov/pubmed/20223009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-4-1-7
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