Distinct responses to hypoxia in subpopulations of distal pulmonary artery cells contribute to pulmonary vascular remodeling in emphysema

We have shown previously that hypoxia inhibits the growth of distal human pulmonary artery smooth muscle cells (PASMC) isolated under standard normoxic conditions (PASMC(norm)). By contrast, a subpopulation of PASMC, isolated through survival selection under hypoxia was found to proliferate in respo...

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Autori principali: Howard, L. S., Crosby, A., Vaughan, P., Sobolewski, A., Southwood, M., Foster, M. L., Chilvers, E. R., Morrell, N. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Medknow Publications & Media Pvt Ltd 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401878/
https://ncbi.nlm.nih.gov/pubmed/22837865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.97616
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