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Distinct responses to hypoxia in subpopulations of distal pulmonary artery cells contribute to pulmonary vascular remodeling in emphysema

We have shown previously that hypoxia inhibits the growth of distal human pulmonary artery smooth muscle cells (PASMC) isolated under standard normoxic conditions (PASMC(norm)). By contrast, a subpopulation of PASMC, isolated through survival selection under hypoxia was found to proliferate in respo...

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Detalhes bibliográficos
Main Authors: Howard, L. S., Crosby, A., Vaughan, P., Sobolewski, A., Southwood, M., Foster, M. L., Chilvers, E. R., Morrell, N. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401878/
https://ncbi.nlm.nih.gov/pubmed/22837865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.97616
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