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Trifluoromethoxyl Substituted Phenylethylene Diamines as High Affinity σ Receptor Ligands with Potent Anti-Cocaine Actions

The phenylethylene diamines are a class of σ receptor ligands with excellent selectivity over other biological systems and with anti-cocaine actions that involve antagonism of σ(1) receptors. In order to increase the potency of the aromatic methoxyl substituted analogues, trifluoromethoxyl groups we...

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Detalhes bibliográficos
Main Authors: Smith, Trudy A., Yang, Xiaowen, Wu, Huifang, Pouw, Buddy, Matsumoto, Rae R., Coop, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401596/
https://ncbi.nlm.nih.gov/pubmed/18461921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm7013666
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