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Elimination of the Actin-Binding Domain in Kelch-Like 1 Protein Induces T-Type Calcium Channel Modulation Only in the Presence of Action Potential Waveforms
The Kelch-like 1 protein (KLHL1) is a neuronal actin-binding protein that modulates calcium channel function. It increases the current density of Ca(v)3.2 (α (1H)) calcium channels via direct interaction with α (1H) and actin-F, resulting in biophysical changes in Ca(v)3.2 currents and an increase i...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Hindawi Publishing Corporation
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401526/ https://ncbi.nlm.nih.gov/pubmed/22848812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/505346 |
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