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Activated ERK2 is a Monomer in vitro with or without Divalent Cations and when Complexed to the Cytoplasmic Scaffold PEA15

The extracellular signal-regulated protein kinase, ERK2, fully activated by phosphorylation and without a His(6)-tag, shows little tendency to dimerize with or without either calcium or magnesium ions when analyzed by light scattering or analytical ultracentrifugation. Light scattering shows that ~...

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Detalhes bibliográficos
Main Authors: Kaoud, Tamer S., Devkota, Ashwini K., Harris, Richard, Rana, Mitra S., Abramczyk, Olga, Warthaka, Mangalika, Lee, Sunbae, Girvin, Mark E., Riggs, Austen F., Dalby, Kevin N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401516/
https://ncbi.nlm.nih.gov/pubmed/21506533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200202y
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