Yields of damage to C4′ deoxyribose and to pyrimidines in pUC18 by the direct effect of ionizing radiation

Our mechanistic understanding of damage formation in DNA by the direct effect relies heavily on what is known of free radical intermediates studied by EPR spectroscopy. Bridging this information to stable product formation requires methods with comparable sensitivities, a criterion met by the (32)P-...

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Bibliografiska uppgifter
Huvudupphovsmän: Peoples, Anita R., Lee, Jane, Weinfeld, Michael, Milligan, Jamie R., Bernhard, William A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Genome Integrity, Repair and Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401456/
https://ncbi.nlm.nih.gov/pubmed/22467205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks271
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