The Epithelial-Mesenchymal Transition (EMT) Regulatory Factor SLUG (SNAI2) Is a Downstream Target of SPARC and AKT in Promoting Melanoma Cell Invasion

During progression of melanoma, malignant melanocytes can be reprogrammed into mesenchymal-like cells through a process similar to epithelial-mesenchymal transition (EMT), which is associated with downregulation of the junctional protein E-cadherin and acquisition of a migratory phenotype. Recent ev...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fenouille, Nina, Tichet, Mélanie, Dufies, Maeva, Pottier, Anaïs, Mogha, Ariane, Soo, Julia K., Rocchi, Stéphane, Mallavialle, Aude, Galibert, Marie-Dominique, Khammari, Amir, Lacour, Jean-Philippe, Ballotti, Robert, Deckert, Marcel, Tartare-Deckert, Sophie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401237/
https://ncbi.nlm.nih.gov/pubmed/22911700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040378
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