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Engineering strategies to recapitulate epithelial morphogenesis within synthetic 3 dimensional extracellular matrix with tunable mechanical properties

The mechanical properties (e.g. stiffness) of the extracellular matrix (ECM) influence cell fate and tissue morphogenesis and contribute to disease progression. Nevertheless, our understanding of the mechanisms by which ECM rigidity modulates cell behavior and fate remains rudimentary. To address th...

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Библиографические подробности
Главные авторы: Miroshnikova, Y.A., Jorgens, D.M., Spirio, L., Auer, M., Sieminski-Sarang, A.L., Weaver, V.M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401181/
https://ncbi.nlm.nih.gov/pubmed/21441648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/8/2/026013
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