A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model

Better understanding of the biophysical and biochemical cues of the tumor extracellular matrix environment that influence metastasis may have important implications for new cancer therapeutics. Initial exploration into this question has used naturally derived protein matrices that suffer from variab...

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Main Authors: Gill, Bartley J., Gibbons, Don L., Roudsari, Laila C., Saik, Jennifer E., Rizvi, Zain H., Roybal, Jonathon D., Kurie, Jonathan M., West, Jennifer L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632398/
https://ncbi.nlm.nih.gov/pubmed/22952217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0895
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