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Metastatic melanoma and vemurafenib: novel approaches

Metastatic melanoma (MM) presents a treatment challenge to oncologists worldwide. Dacarbazine is the first line chemotherapy treatment for MM, though the overall response rates are very poor. Recently, the v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600 mutation was found to play a main r...

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Detalhes bibliográficos
Autor principal: De Mello, Ramon Andrade
Formato: Artigo
Idioma:Inglês
Publicado em: PAGEPress Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401159/
https://ncbi.nlm.nih.gov/pubmed/22826788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/rt.2012.e31
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