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Self-Renewal of the Long-Term Reconstituting Subset of Hematopoietic Stem Cells is Regulated by Ikaros

Hematopoietic stem cells (HSCs) are rare, ancestral cells that underlie the development, homeostasis, aging, and regeneration of the blood. Here we show the chromatin-associated protein Ikaros is a crucial self-renewal regulator of the long-term (LT) reconstituting subset of HSCs. Ikaros, and associ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Papathanasiou, Peter, Attema, Joanne L., Karsunky, Holger, Hosen, Naoki, Sontani, Yovina, Hoyne, Gerard F., Tunningley, Robert, Smale, Stephen T., Weissman, Irving L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401049/
https://ncbi.nlm.nih.gov/pubmed/19816952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.232
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