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Live Attenuated Lentivirus Infection Elicits Polyfunctional Simian Immunodeficiency Virus Gag-Specific CD8(+) T Cells with Reduced Apoptotic Susceptibility in Rhesus Macaques that Control Virus Replication after Challenge with Pathogenic SIVmac239

HIV-specific CD8(+) T cells that secrete multiple cytokines in response to Ag stimulation are associated with the control of virus replication during chronic HIV infection. To determine whether the presence of polyfunctional CD8(+) T cell responses distinguishes protected and unprotected monkeys in...

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Autori principali: Genescà, Meritxell, Rourke, Tracy, Li, Jun, Bost, Kristen, Chohan, Barinderpaul, McChesney, Michael B., Miller, Christopher J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401023/
https://ncbi.nlm.nih.gov/pubmed/17878372
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