Targeted lymph-node immunization with whole inactivated simian immunodeficiency virus (SIV) or envelope and core subunit antigen vaccines does not reliably protect rhesus macaques from vaginal challenge with SIV(mac251)

OBJECTIVE: Sexual transmission of HIV is the most common route of HIV transmission throughout the world. To prevent sexually transmitted HIV infection, a vaccine is urgently needed. A previous report demonstrated the targeted immunization of the iliac lymph nodes with simian immunodeficiency virus (...

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Autores principales: Lü, Xusheng, Kiyono, Hiroshi, Lu, Ding, Kawabata, Shigetada, Torten, Judy, Srinivasan, Seema, Dailey, Peter J., McGhee, Jerry R., Lehner, Thomas, Miller, Christopher J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401021/
https://ncbi.nlm.nih.gov/pubmed/9456249
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