Penitrem A as a Tool for Understanding the Role of Large Conductance Ca(2+)/Voltage-Sensitive K(+) Channels in Vascular Function

Large conductance, Ca(2+)/voltage-sensitive K(+) channels (BK channels) are well characterized, but their physiological roles, often determined through pharmacological manipulation, are less clear. Iberiotoxin is considered the “gold standard” antagonist, but cost and membrane-impermeability limit i...

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Bibliografiska uppgifter
Huvudupphovsmän: Asano, Shinichi, Bratz, Ian N., Berwick, Zachary C., Fancher, Ibra S., Tune, Johnathan D., Dick, Gregory M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2012
Ämnen:
Cardiovascular
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400808/
https://ncbi.nlm.nih.gov/pubmed/22580348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.191072
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