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Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

Neurons are critically dependent on mitochondrial integrity based on specific morphological, biochemical, and physiological features. They are characterized by high rates of metabolic activity and need to respond promptly to activity-dependent fluctuations in bioenergetic demand. The dimensions and...

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Detalhes bibliográficos
Main Authors: Exner, Nicole, Lutz, Anne Kathrin, Haass, Christian, Winklhofer, Konstanze F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400019/
https://ncbi.nlm.nih.gov/pubmed/22735187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.170
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