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The TLR9 agonist, CpG-ODN 1826, ameliorates cardiac dysfunction after trauma-hemorrhage

Cardiovascular collapse is the major factor contributing to the mortality of trauma-hemorrhage (T-H) patients. Toll-like receptors (TLRs) play a critical role in T-H-induced cardiac dysfunction. This study evaluated the role of TLR9 agonist, CpG-ODN 1826, in cardiac functional recovery after T-H. Tr...

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Bibliographic Details
Main Authors: Zhang, Xia, Gao, Ming, Ha, Tuanzhu, Kalbfleisch, John H., Williams, David L., Li, Chuanfu, Kao, Race L.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399944/
https://ncbi.nlm.nih.gov/pubmed/22576005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31825ce0de
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