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Loop 7 of E2 Enzymes: An Ancestral Conserved Functional Motif Involved in the E2-Mediated Steps of the Ubiquitination Cascade

The ubiquitin (Ub) system controls almost every aspect of eukaryotic cell biology. Protein ubiquitination depends on the sequential action of three classes of enzymes (E1, E2 and E3). E2 Ub-conjugating enzymes have a central role in the ubiquitination pathway, interacting with both E1 and E3, and in...

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Dettagli Bibliografici
Autori principali: Papaleo, Elena, Casiraghi, Nicola, Arrigoni, Alberto, Vanoni, Marco, Coccetti, Paola, De Gioia, Luca
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399832/
https://ncbi.nlm.nih.gov/pubmed/22815819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040786
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