Rituximab inhibits Kv1.3 channels in human B lymphoma cells via activation of FcγRIIB receptors

Kv1.3 channels play an important role in modulating lymphocyte proliferation and apoptosis. We hypothesized that Kv1.3 channels in B lymphocytes might be regulated by rituximab, an antibody to CD20, a drug for treatments of B-cell lymphomas and autoimmune diseases. Using both whole-cell and cell-att...

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Detalhes bibliográficos
Main Authors: Wang, Li-Hua, Wang, Ning, Lu, Xiao-Yu, Liu, Bing-Chen, Yanda, Murali K., Song, John Z., Dai, Helena M., Sun, Yu-Liang, Bao, Hui-Fang, Eaton, Douglas C., Ma, He-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399683/
https://ncbi.nlm.nih.gov/pubmed/22192444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.11.012
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