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Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD mice

During normal aging, men experience a significant decline in testosterone levels and a compensatory elevation in levels of gonadotropin luteinizing hormone (LH). Both low testosterone and elevated LH have been identified as significant risk factors for the development of Alzheimer's disease (AD...

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Main Authors: Rosario, Emily R., Carroll, Jenna C., Pike, Christian J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399667/
https://ncbi.nlm.nih.gov/pubmed/22587890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.05.011
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