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Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways

Normal, age-related depletion of the androgen testosterone is a risk factor for Alzheimer’s disease (AD) in men. Previously, we reported that experimental androgen depletion significantly accelerates development of AD-like neuropathology in the 3xTg-AD triple-transgenic mouse model of AD, an effect...

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Detalhes bibliográficos
Main Authors: Rosario, Emily R., Carroll, Jenna, Pike, Christian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965035/
https://ncbi.nlm.nih.gov/pubmed/20807511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.08.068
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