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Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways
Normal, age-related depletion of the androgen testosterone is a risk factor for Alzheimer’s disease (AD) in men. Previously, we reported that experimental androgen depletion significantly accelerates development of AD-like neuropathology in the 3xTg-AD triple-transgenic mouse model of AD, an effect...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965035/ https://ncbi.nlm.nih.gov/pubmed/20807511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.08.068 |
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