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Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways
Normal, age-related depletion of the androgen testosterone is a risk factor for Alzheimer’s disease (AD) in men. Previously, we reported that experimental androgen depletion significantly accelerates development of AD-like neuropathology in the 3xTg-AD triple-transgenic mouse model of AD, an effect...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965035/ https://ncbi.nlm.nih.gov/pubmed/20807511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.08.068 |
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