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Genesis of tramsmissible protein states via deformed templating
Prion replication occurs via a template-assisted mechanism, which postulates that the folding pattern of a newly recruited polypeptide chain accurately reproduces that of a template. The concept of prion-like template-assisted propagation of an abnormal protein conformation has been expanded to amyl...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399541/ https://ncbi.nlm.nih.gov/pubmed/22561163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19930 |
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