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The Same Primary Structure of the Prion Protein Yields Two Distinct Self-propagating States

The question of whether distinct self-propagating structures could be formed within the same amino acid sequence in the absence of external cofactors or templates has important implications for a number of issues, including the origin of prion strains and the engineering of smart, self-assembling pe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Makarava, Natallia, Baskakov, Ilia V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414308/
https://ncbi.nlm.nih.gov/pubmed/18400757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800562200
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