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The Same Primary Structure of the Prion Protein Yields Two Distinct Self-propagating States
The question of whether distinct self-propagating structures could be formed within the same amino acid sequence in the absence of external cofactors or templates has important implications for a number of issues, including the origin of prion strains and the engineering of smart, self-assembling pe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2414308/ https://ncbi.nlm.nih.gov/pubmed/18400757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800562200 |
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