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Precursor microRNA Programmed Silencing Complex Assembly Pathways in Mammals
Assembly of microRNA Ribonucleoproteins (miRNPs) or RNA-Induced Silencing Complexes (RISCs) is essential for the function of miRNAs and initiates from processing of precursor miRNAs (pre-miRNAs) by Dicer or by Ago2. Here, we report an in-vitro miRNP/RISC assembly assay programmed by pre-miRNAs from...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399505/ https://ncbi.nlm.nih.gov/pubmed/22503104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.03.010 |
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