Quantitative and Automated High-throughput Genome-wide RNAi Screens in C. elegans

RNA interference is a powerful method to understand gene function, especially when conducted at a whole-genome scale and in a quantitative context. In C. elegans, gene function can be knocked down simply and efficiently by feeding worms with bacteria expressing a dsRNA corresponding to a specific ge...

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Main Authors: Squiban, Barbara, Belougne, Jérôme, Ewbank, Jonathan, Zugasti, Olivier
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2012
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399495/
https://ncbi.nlm.nih.gov/pubmed/22395785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3448
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