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Activation of a G protein-coupled receptor by its endogenous ligand triggers the Caenorhabditis elegans innate immune response
Immune defenses are triggered by microbe-associated molecular patterns or as a result of damage to host cells. The elicitors of immune responses in the nematode Caenorhabditis elegans are unclear. Using a genome-wide RNAi screen, we identify the G-protein coupled receptor (GPCR) DCAR-1 as being requ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139443/ https://ncbi.nlm.nih.gov/pubmed/25086774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2957 |
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