Downregulation of Endothelial MicroRNA-200b Supports Cutaneous Wound Angiogenesis By Desilencing GATA Binding Protein 2 and Vascular Endothelial Growth Factor Receptor 2

OBJECTIVE: MicroRNAs (miRs) regulate angiogenesis by posttranscriptional silencing of target genes. The significance of angiostatic miR-200b in switching on skin wound angiogenesis was tested. METHODS AND RESULTS: Wounding caused imminent and transient downregulation of miR-200b in dermal wound-edge...

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Detaylı Bibliyografya
Asıl Yazarlar: Chan, Yuk Cheung, Roy, Sashwati, Khanna, Savita, Sen, Chandan K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399424/
https://ncbi.nlm.nih.gov/pubmed/22499991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.248583
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