The MicroRNA miR-199a-5p Down-regulation Switches on Wound Angiogenesis by Derepressing the v-ets Erythroblastosis Virus E26 Oncogene Homolog 1-Matrix Metalloproteinase-1 Pathway

miR-199a-5p plays a critical role in controlling cardiomyocyte survival. However, its significance in endothelial cell biology remains ambiguous. Here, we report the first evidence that miR-199a-5p negatively regulates angiogenic responses by directly targeting v-ets erythroblastosis virus E26 oncog...

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Bibliographic Details
Main Authors: Chan, Yuk Cheung, Roy, Sashwati, Huang, Yue, Khanna, Savita, Sen, Chandan K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510806/
https://ncbi.nlm.nih.gov/pubmed/23060436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413294
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