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Competitive Antigen Panning for Selection of HIV-1 Neutralizing Human Monoclonal Antibodies Specific for gp41

HIV envelope glycoprotein (Env) is composed of two non-covalently associated subunits: gp120 and gp41. Panning of phage-displayed antibody libraries against gp140 (covalently linked gp120 and the extracellular portion of gp41) has resulted mostly in selection of anti-gp120 antibodies. Native gp41 in...

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Hlavní autoři: Zhang, Mei-Yun, Dimitrov, Dimiter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399416/
https://ncbi.nlm.nih.gov/pubmed/19252830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-554-1_9
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