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Quantitative comparison of randomization designs in sequential clinical trials based on treatment balance and allocation randomness

To evaluate the performance of randomization designs under various parameter settings and trial sample sizes, and identify optimal designs with respect to both treatment imbalance and allocation randomness, we evaluate 260 design scenarios from 14 randomization designs under 15 sample sizes range fr...

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Bibliographic Details
Main Authors: Zhao, Wenle, Weng, Yanqiu, Wu, Qi, Palesch, Yuko
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399213/
https://ncbi.nlm.nih.gov/pubmed/21544929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.493
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