Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia

Women over 50 years of age account for 75% of new breast cancer diagnoses, and the majority of these tumors are of a luminal subtype. Although age-associated changes, including endocrine profiles and alterations within the breast microenvironment, increase cancer risk, an understanding of the molecu...

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Detalhes bibliográficos
Main Authors: Garbe, James C, Pepin, Francois, Pelissier, Fanny, Sputova, Klara, Fridriksdottir, Agla J, Guo, Diana E, Villadsen, Rene, Park, Morag, Petersen, Ole W, Borowsky, Alexander D., Stampfer, Martha R, LaBarge, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399034/
https://ncbi.nlm.nih.gov/pubmed/22552289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0157
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